Perturbed Redox Signaling Exacerbates a Mitochondrial Myopathy

Alternative oxidases (AOXs) bypass respiratory complexes III and IV by transferring electrons from coenzyme Q directly to O(2). They have therefore been proposed as a potential therapeutic tool for mitochondrial diseases. We crossed the severely myopathic skeletal muscle-specific COX15 knockout (KO)...

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Detalles Bibliográficos
Autores principales: Dogan, Sukru Anil, Cerutti, Raffaele, Benincá, Cristiane, Brea-Calvo, Gloria, Jacobs, Howard Trevor, Zeviani, Massimo, Szibor, Marten, Viscomi, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224544/
https://www.ncbi.nlm.nih.gov/pubmed/30122554
http://dx.doi.org/10.1016/j.cmet.2018.07.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224544/
https://www.ncbi.nlm.nih.gov/pubmed/30122554
http://dx.doi.org/10.1016/j.cmet.2018.07.012

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