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A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

Numerous mechanisms to support cells under conditions of transient nutrient starvation have been described. Several functions of the tumor-suppressor protein p53 can contribute to the adaptation of cells to metabolic stress and help cancer cell survival under nutrient-limiting conditions. We show he...

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Detalles Bibliográficos
Autores principales: Tajan, Mylène, Hock, Andreas K., Blagih, Julianna, Robertson, Neil A., Labuschagne, Christiaan F., Kruiswijk, Flore, Humpton, Timothy J., Adams, Peter D., Vousden, Karen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224545/
https://www.ncbi.nlm.nih.gov/pubmed/30122553
http://dx.doi.org/10.1016/j.cmet.2018.07.005