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Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts
Progression of multiple myeloma (MM) is largely dependent on the bone marrow (BM) microenvironment wherein communication through different factors including extracellular vesicles takes place. This cross-talk not only leads to drug resistance but also to the development of osteolysis. Targeting vesi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224554/ https://www.ncbi.nlm.nih.gov/pubmed/30409995 http://dx.doi.org/10.1038/s41408-018-0139-7 |