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Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts

Progression of multiple myeloma (MM) is largely dependent on the bone marrow (BM) microenvironment wherein communication through different factors including extracellular vesicles takes place. This cross-talk not only leads to drug resistance but also to the development of osteolysis. Targeting vesi...

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Detalles Bibliográficos
Autores principales: Faict, Sylvia, Muller, Joséphine, De Veirman, Kim, De Bruyne, Elke, Maes, Ken, Vrancken, Louise, Heusschen, Roy, De Raeve, Hendrik, Schots, Rik, Vanderkerken, Karin, Caers, Jo, Menu, Eline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224554/
https://www.ncbi.nlm.nih.gov/pubmed/30409995
http://dx.doi.org/10.1038/s41408-018-0139-7