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Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo

The tetanus toxin C-fragment is a non-toxic peptide that can be transported from peripheral axons into spinal motoneurons. In in vitro experiments it has been shown that this peptide activates signaling pathways associated with Trk receptors, leading to cellular survival. Because motoneuron degenera...

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Detalles Bibliográficos
Autores principales: Netzahualcoyotzi, Citlalli, Tapia, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224557/
https://www.ncbi.nlm.nih.gov/pubmed/30410110
http://dx.doi.org/10.1038/s41598-018-35027-w