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Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo
The tetanus toxin C-fragment is a non-toxic peptide that can be transported from peripheral axons into spinal motoneurons. In in vitro experiments it has been shown that this peptide activates signaling pathways associated with Trk receptors, leading to cellular survival. Because motoneuron degenera...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224557/ https://www.ncbi.nlm.nih.gov/pubmed/30410110 http://dx.doi.org/10.1038/s41598-018-35027-w |