Src-transformed cells hijack mitosis to extrude from the epithelium

At the initial stage of carcinogenesis single mutated cells appear within an epithelium. Mammalian in vitro experiments show that potentially cancerous cells undergo live apical extrusion from normal monolayers. However, the mechanism underlying this process in vivo remains poorly understood. Mosaic...

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Detalles Bibliográficos
Autores principales: Anton, Katarzyna A., Kajita, Mihoko, Narumi, Rika, Fujita, Yasuyuki, Tada, Masazumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224566/
https://www.ncbi.nlm.nih.gov/pubmed/30410020
http://dx.doi.org/10.1038/s41467-018-07163-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224566/
https://www.ncbi.nlm.nih.gov/pubmed/30410020
http://dx.doi.org/10.1038/s41467-018-07163-4

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