Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2

The complex immune tumour microenvironment requires an equally complex immunotherapy approach, especially when the cancer-immune set point is non-inflamed. Oncolytic viruses expressing immune activating cytokines might optimally modify the immune microenvironment and improve the antitumour effects....

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Detalles Bibliográficos
Autores principales: Liu, Zuqiang, Ge, Yan, Wang, Haiyan, Ma, Congrong, Feist, Mathilde, Ju, Songguang, Guo, Z. Sheng, Bartlett, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224581/
https://www.ncbi.nlm.nih.gov/pubmed/30410056
http://dx.doi.org/10.1038/s41467-018-06954-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224581/
https://www.ncbi.nlm.nih.gov/pubmed/30410056
http://dx.doi.org/10.1038/s41467-018-06954-z

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