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Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2
The complex immune tumour microenvironment requires an equally complex immunotherapy approach, especially when the cancer-immune set point is non-inflamed. Oncolytic viruses expressing immune activating cytokines might optimally modify the immune microenvironment and improve the antitumour effects....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224581/ https://www.ncbi.nlm.nih.gov/pubmed/30410056 http://dx.doi.org/10.1038/s41467-018-06954-z |