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miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer

Epithelial ovarian carcinoma (EOC) is the most lethal gynecologic malignancy. However, the molecular mechanisms remain unclear. In this study, we found that miR-146b was downregulated in EOC and its expression level was negatively correlated with the pathological staging. Follow-up functional experi...

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Detalles Bibliográficos
Autores principales: Yan, Meina, Yang, Xinxin, Shen, Rong, Wu, Chengjiang, Wang, Hui, Ye, Qing, Yang, Peifang, Zhang, Lubin, Chen, Miao, Wan, Bing, Zhang, Qinqin, Xia, Sheng, Lu, Xiaodong, Shao, Genbao, Zhou, Xiaoming, Yu, Jun, Shao, Qixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224598/
https://www.ncbi.nlm.nih.gov/pubmed/30409964
http://dx.doi.org/10.1038/s41419-018-1093-9