Structural basis for the second step of group II intron splicing

The group II intron and the spliceosome share a common active site architecture and are thought to be evolutionarily related. Here we report the 3.7 Å crystal structure of a eukaryotic group II intron in the lariat-3′ exon form, immediately preceding the second step of splicing, analogous to the spl...

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Detalles Bibliográficos
Autores principales: Chan, Russell T., Peters, Jessica K., Robart, Aaron R., Wiryaman, Timothy, Rajashankar, Kanagalaghatta R., Toor, Navtej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224600/
https://www.ncbi.nlm.nih.gov/pubmed/30410046
http://dx.doi.org/10.1038/s41467-018-06678-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224600/
https://www.ncbi.nlm.nih.gov/pubmed/30410046
http://dx.doi.org/10.1038/s41467-018-06678-0

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