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Structural basis for the second step of group II intron splicing
The group II intron and the spliceosome share a common active site architecture and are thought to be evolutionarily related. Here we report the 3.7 Å crystal structure of a eukaryotic group II intron in the lariat-3′ exon form, immediately preceding the second step of splicing, analogous to the spl...
Autores principales: | Chan, Russell T., Peters, Jessica K., Robart, Aaron R., Wiryaman, Timothy, Rajashankar, Kanagalaghatta R., Toor, Navtej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224600/ https://www.ncbi.nlm.nih.gov/pubmed/30410046 http://dx.doi.org/10.1038/s41467-018-06678-0 |
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