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TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation

The Warburg effect is a prominent metabolic feature associated with neoplastic diseases; however, the underlying mechanism remains incompletely understood. TAp73, a structural homolog of the tumor suppressor p53, is frequently overexpressed in human tumors, indicating a proliferative advantage that...

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Detalles Bibliográficos
Autores principales: Li, Le, Li, Lijia, Li, Wei, Chen, Taiqi, Bin Zou, Zhao, Lina, Wang, Huili, Wang, Xueying, Xu, Lina, Liu, Xiaohui, Wang, Dong, Li, Bo, Mak, Tak W., Du, Wenjing, Yang, Xiaolu, Jiang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224601/
https://www.ncbi.nlm.nih.gov/pubmed/30409970
http://dx.doi.org/10.1038/s41467-018-07127-8