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TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation
The Warburg effect is a prominent metabolic feature associated with neoplastic diseases; however, the underlying mechanism remains incompletely understood. TAp73, a structural homolog of the tumor suppressor p53, is frequently overexpressed in human tumors, indicating a proliferative advantage that...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224601/ https://www.ncbi.nlm.nih.gov/pubmed/30409970 http://dx.doi.org/10.1038/s41467-018-07127-8 |