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Dynamics of Chromatin Fibers: Comparison of Monte Carlo Simulations with Force Spectroscopy

To elucidate conformational dynamics of chromatin fibers, we compared available force-spectroscopy measurements with extensive Monte Carlo simulations of nucleosome arrays under external force. Our coarse-grained model of chromatin includes phenomenological energy terms for the DNA-histone adhesion...

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Detalles Bibliográficos
Autores principales: Norouzi, Davood, Zhurkin, Victor B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225046/
https://www.ncbi.nlm.nih.gov/pubmed/30236784
http://dx.doi.org/10.1016/j.bpj.2018.06.032