Comparative Studies of the Dynamics Effects of BAY60-2770 and BAY58-2667 Binding with Human and Bacterial H-NOX Domains

Soluble guanylate cyclase (sGC) is a key enzyme implicated in various physiological processes such as vasodilation, thrombosis and platelet aggregation. The enzyme’s Heme-Nitric oxide/Oxygen (H-NOX) binding domain is the only sensor of nitric oxide (NO) in humans, which on binding with NO activates...

Descripción completa

Detalles Bibliográficos
Autores principales: Rehan Khalid, Rana, Tahir ul Qamar, Muhammad, Maryam, Arooma, Ashique, Ayesha, Anwar, Farooq, H. Geesi, Mohammed, Siddiqi, Abdul Rauf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225106/
https://www.ncbi.nlm.nih.gov/pubmed/30149624
http://dx.doi.org/10.3390/molecules23092141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225106/
https://www.ncbi.nlm.nih.gov/pubmed/30149624
http://dx.doi.org/10.3390/molecules23092141

Ejemplares similares