Oxadiazole/Pyridine-Based Ligands: A Structural Tuning for Enhancing G-Quadruplex Binding

Non-macrocyclic heteroaryls represent a valuable class of ligands for nucleic acid recognition. In this regard, non-macrocyclic pyridyl polyoxazoles and polyoxadiazoles were recently identified as selective G-quadruplex stabilizing compounds with high cytotoxicity and promising anticancer activity....

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Detalles Bibliográficos
Autores principales: Doria, Filippo, Pirota, Valentina, Petenzi, Michele, Teulade-Fichou, Marie-Paule, Verga, Daniela, Freccero, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225118/
https://www.ncbi.nlm.nih.gov/pubmed/30154319
http://dx.doi.org/10.3390/molecules23092162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225118/
https://www.ncbi.nlm.nih.gov/pubmed/30154319
http://dx.doi.org/10.3390/molecules23092162

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