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Oxadiazole/Pyridine-Based Ligands: A Structural Tuning for Enhancing G-Quadruplex Binding

Non-macrocyclic heteroaryls represent a valuable class of ligands for nucleic acid recognition. In this regard, non-macrocyclic pyridyl polyoxazoles and polyoxadiazoles were recently identified as selective G-quadruplex stabilizing compounds with high cytotoxicity and promising anticancer activity....

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Detalles Bibliográficos
Autores principales:	Doria, Filippo, Pirota, Valentina, Petenzi, Michele, Teulade-Fichou, Marie-Paule, Verga, Daniela, Freccero, Mauro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225118/ https://www.ncbi.nlm.nih.gov/pubmed/30154319 http://dx.doi.org/10.3390/molecules23092162

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