Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis †

Two 3D quantitative structure–activity relationships (3D-QSAR) models for predicting Cannabinoid receptor 1 and 2 (CB(1) and CB(2)) ligands have been produced by way of creating a practical tool for the drug-design and optimization of CB(1) and CB(2) ligands. A set of 312 molecules have been used to...

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Detalles Bibliográficos
Autores principales: Floresta, Giuseppe, Apirakkan, Orapan, Rescifina, Antonio, Abbate, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225167/
https://www.ncbi.nlm.nih.gov/pubmed/30200181
http://dx.doi.org/10.3390/molecules23092183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225167/
https://www.ncbi.nlm.nih.gov/pubmed/30200181
http://dx.doi.org/10.3390/molecules23092183

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