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Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis †

Two 3D quantitative structure–activity relationships (3D-QSAR) models for predicting Cannabinoid receptor 1 and 2 (CB(1) and CB(2)) ligands have been produced by way of creating a practical tool for the drug-design and optimization of CB(1) and CB(2) ligands. A set of 312 molecules have been used to...

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Detalles Bibliográficos
Autores principales:	Floresta, Giuseppe, Apirakkan, Orapan, Rescifina, Antonio, Abbate, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225167/ https://www.ncbi.nlm.nih.gov/pubmed/30200181 http://dx.doi.org/10.3390/molecules23092183

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