Design, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents

Three series of N-(pyrazin-2-yl)benzamides were designed as retro-amide analogues of previously published N-phenylpyrazine-2-carboxamides with in vitro antimycobacterial activity. The synthesized retro-amides were evaluated for in vitro growth inhibiting activity against Mycobacterium tuberculosis H...

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Detalles Bibliográficos
Autores principales: Zitko, Jan, Mindlová, Alžběta, Valášek, Ondřej, Jand’ourek, Ondřej, Paterová, Pavla, Janoušek, Jiří, Konečná, Klára, Doležal, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225228/
https://www.ncbi.nlm.nih.gov/pubmed/30231544
http://dx.doi.org/10.3390/molecules23092390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225228/
https://www.ncbi.nlm.nih.gov/pubmed/30231544
http://dx.doi.org/10.3390/molecules23092390

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