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Pomolic Acid Ameliorates Fibroblast Activation and Renal Interstitial Fibrosis through Inhibition of SMAD-STAT Signaling Pathways

Fibrosis is a common pathological feature in most kinds of chronic kidney disease. Transforming growth factor β1 (TGF-β1) signaling is the master pathway regulating kidney fibrosis pathogenesis, in which mothers against decapentaplegic homolog 3 (SMAD3) with signal transducer and activator of transc...

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Detalles Bibliográficos
Autores principales: Park, Ji-Hyun, Jang, Kyung Mi, An, Hyun Jin, Kim, Jung-Yeon, Gwon, Mi-Gyeong, Gu, Hyemin, Park, Byoungduck, Park, Kwan-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225234/
https://www.ncbi.nlm.nih.gov/pubmed/30177595
http://dx.doi.org/10.3390/molecules23092236