d-Amino Acid Pseudopeptides as Potential Amyloid-Beta Aggregation Inhibitors

A causative factor for neurotoxicity associated with Alzheimer’s disease is the aggregation of the amyloid-β (Aβ) peptide into soluble oligomers. Two all d-amino acid pseudo-peptides, SGB1 and SGD1, were designed to stop the aggregation. Molecular dynamics (MD) simulations have been carried out to s...

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Detalles Bibliográficos
Autores principales: Mehrazma, Banafsheh, Opare, Stanley, Petoyan, Anahit, Rauk, Arvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225248/
https://www.ncbi.nlm.nih.gov/pubmed/30231520
http://dx.doi.org/10.3390/molecules23092387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225248/
https://www.ncbi.nlm.nih.gov/pubmed/30231520
http://dx.doi.org/10.3390/molecules23092387

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