Synthesis and Biological Evaluation of Novel Alkyl Amine Substituted Icariside II Derivatives as Potential Anticancer Agents

A series of novel alkyl amine-substituted icariside II (ICA II) derivatives were synthesized by Mannich reactions at the 6-C position (compounds 4a–d) and changing the carbon chain length at the 7-OH position (compounds 7a–h), and their in vitro antitumor activity towards human breast cancer lines (...

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Detalles Bibliográficos
Autores principales: Wu, Tong, Li, Ting, Kang, Ya-Nan, Liu, Li, Wang, Xi-Man, Lan, Jin-Shuai, Ding, Yue, Zhang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225249/
https://www.ncbi.nlm.nih.gov/pubmed/30150543
http://dx.doi.org/10.3390/molecules23092146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225249/
https://www.ncbi.nlm.nih.gov/pubmed/30150543
http://dx.doi.org/10.3390/molecules23092146

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