Imaging of Human Insulin Secreting Cells with Gd-DOTA-P88, a Paramagnetic Contrast Agent Targeting the Beta Cell Biomarker FXYD2γa

Non-invasive imaging and quantification of human beta cell mass remains a major challenge. We performed pre-clinical in vivo validation of a peptide previously discovered by our group, namely, P88 that targets a beta cell specific biomarker, FXYD2γa. We conjugated P88 with DOTA and then complexed it...

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Detalles Bibliográficos
Autores principales: Demine, Stéphane, Balhuizen, Alexander, Debaille, Vinciane, Joosten, Lieke, Fereau, Maïté, Chilla, Satya Narayana Murthy, Millard, Isabelle, Scharfmann, Raphaël, Egrise, Dominique, Goldman, Serge, Marchetti, Piero, Gotthardt, Martin, Laurent, Sophie, Burtea, Carmen, Eizirik, Decio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225257/
https://www.ncbi.nlm.nih.gov/pubmed/30134599
http://dx.doi.org/10.3390/molecules23092100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225257/
https://www.ncbi.nlm.nih.gov/pubmed/30134599
http://dx.doi.org/10.3390/molecules23092100

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