Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages

Heat shock cognate protein 70 (HSC70), a molecular chaperone, is constitutively expressed by mammalian cells to regulate various cellular functions. It is associated with many diseases and is a potential therapeutic target. Although HSC70 also possesses an anti-inflammatory action, the mechanism of...

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Detalles Bibliográficos
Autores principales: Sulistyowati, Erna, Lee, Mei-Yueh, Wu, Lin-Chi, Hsu, Jong-Hau, Dai, Zen-Kong, Wu, Bin-Nan, Lin, Ming-Chung, Yeh, Jwu-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225271/
https://www.ncbi.nlm.nih.gov/pubmed/30142934
http://dx.doi.org/10.3390/molecules23092124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225271/
https://www.ncbi.nlm.nih.gov/pubmed/30142934
http://dx.doi.org/10.3390/molecules23092124

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