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Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages
Heat shock cognate protein 70 (HSC70), a molecular chaperone, is constitutively expressed by mammalian cells to regulate various cellular functions. It is associated with many diseases and is a potential therapeutic target. Although HSC70 also possesses an anti-inflammatory action, the mechanism of...
Autores principales: | Sulistyowati, Erna, Lee, Mei-Yueh, Wu, Lin-Chi, Hsu, Jong-Hau, Dai, Zen-Kong, Wu, Bin-Nan, Lin, Ming-Chung, Yeh, Jwu-Lai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225271/ https://www.ncbi.nlm.nih.gov/pubmed/30142934 http://dx.doi.org/10.3390/molecules23092124 |
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