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Targeting Difficult Protein-Protein Interactions with Plain and General Computational Approaches
Investigating protein-protein interactions (PPIs) holds great potential for therapeutic applications, since they mediate intricate cell signaling networks in physiological and disease states. However, their complex and multifaceted nature poses a major challenge for biochemistry and medicinal chemis...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225287/ https://www.ncbi.nlm.nih.gov/pubmed/30181519 http://dx.doi.org/10.3390/molecules23092256 |