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Development and Evaluation of Minocycline Hydrochloride-Loaded In Situ Cubic Liquid Crystal for Intra-Periodontal Pocket Administration

In the present study, an injectable in situ liquid crystal formulation was developed for local delivery of minocycline hydrochloride (MH) for chronic periodontitis treatment. The physicochemical properties, phase structures, in vitro drug release and pharmacodynamics of in situ liquid crystals were...

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Detalles Bibliográficos
Autores principales: Yang, Zhuanzhuan, Liang, Xin, Jiang, Xiaojing, Guo, Jian, Tao, Yaotian, Wang, Shengmei, Cao, Yingji, Gui, Shuangying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225298/
https://www.ncbi.nlm.nih.gov/pubmed/30200615
http://dx.doi.org/10.3390/molecules23092275