RhoA/ROCK-2 Pathway Inhibition and Tight Junction Protein Upregulation by Catalpol Suppresses Lipopolysaccaride-Induced Disruption of Blood-Brain Barrier Permeability

Lipopolysaccaride (LPS) directly or indirectly injures brain microvascular endothelial cells (BMECs) and damages the intercellular tight junction that gives rise to altered blood-brain barrier (BBB) permeability. Catalpol plays a protective role in LPS-induced injury, but whether catalpol protects a...

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Detalles Bibliográficos
Autores principales: Feng, Shan, Zou, Li, Wang, Hongjin, He, Ran, Liu, Ke, Zhu, Huifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225311/
https://www.ncbi.nlm.nih.gov/pubmed/30227623
http://dx.doi.org/10.3390/molecules23092371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225311/
https://www.ncbi.nlm.nih.gov/pubmed/30227623
http://dx.doi.org/10.3390/molecules23092371

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