Native V. californicum Alkaloid Combinations Induce Differential Inhibition of Sonic Hedgehog Signaling

Veratrum californicum is a rich source of steroidal alkaloids such as cyclopamine, a known inhibitor of the Hedgehog (Hh) signaling pathway. Here we provide a detailed analysis of the alkaloid composition of V. californicum by plant part through quantitative analysis of cyclopamine, veratramine, mul...

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Detalles Bibliográficos
Autores principales: Turner, Matthew W., Cruz, Roberto, Elwell, Jordan, French, John, Mattos, Jared, McDougal, Owen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225318/
https://www.ncbi.nlm.nih.gov/pubmed/30200443
http://dx.doi.org/10.3390/molecules23092222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225318/
https://www.ncbi.nlm.nih.gov/pubmed/30200443
http://dx.doi.org/10.3390/molecules23092222

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