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Native V. californicum Alkaloid Combinations Induce Differential Inhibition of Sonic Hedgehog Signaling
Veratrum californicum is a rich source of steroidal alkaloids such as cyclopamine, a known inhibitor of the Hedgehog (Hh) signaling pathway. Here we provide a detailed analysis of the alkaloid composition of V. californicum by plant part through quantitative analysis of cyclopamine, veratramine, mul...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225318/ https://www.ncbi.nlm.nih.gov/pubmed/30200443 http://dx.doi.org/10.3390/molecules23092222 |