Iodide/H(2)O(2) Catalyzed Intramolecular Oxidative Amination for the Synthesis of 3,2′-Pyrrolidinyl Spirooxindoles

An ammonium iodide/hydrogen peroxide-mediated intramolecular oxidative amination of 3-aminoalkyl-2-oxindoles was achieved, affording the corresponding 3,2′-pyrrolidinyl spirooxindoles and their 6- or 7-membered analogous in moderate to high yields. This metal-free procedure features very mild reacti...

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Detalles Bibliográficos
Autores principales: Gao, Yu-Ting, Jin, Xiao-Yang, Liu, Qi, Liu, An-Di, Cheng, Liang, Wang, Dong, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225319/
https://www.ncbi.nlm.nih.gov/pubmed/30189635
http://dx.doi.org/10.3390/molecules23092265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225319/
https://www.ncbi.nlm.nih.gov/pubmed/30189635
http://dx.doi.org/10.3390/molecules23092265

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