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Characterization of α-Glucosidase Inhibitors from Clinacanthus nutans Lindau Leaves by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Simulation

Background: Clinacanthus nutans (C. nutans) is an Acanthaceae herbal shrub traditionally consumed to treat various diseases including diabetes in Malaysia. This study was designed to evaluate the α-glucosidase inhibitory activity of C. nutans leaves extracts, and to identify the metabolites responsi...

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Detalles Bibliográficos
Autores principales: Murugesu, Suganya, Ibrahim, Zalikha, Ahmed, Qamar-Uddin, Nik Yusoff, Nik-Idris, Uzir, Bisha-Fathamah, Perumal, Vikneswari, Abas, Faridah, Saari, Khozirah, El-Seedi, Hesham, Khatib, Alfi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225325/
https://www.ncbi.nlm.nih.gov/pubmed/30235889
http://dx.doi.org/10.3390/molecules23092402