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Sinomenine Protects Against Morphine Dependence through the NMDAR1/CAMKII/CREB Pathway: A Possible Role of Astrocyte-Derived Exosomes

Sinomenine is a nonaddictive alkaloid used to prevent morphine dependence, even thoughits mechanism isnot fully understood. Astrocytes aggravate the pathological process in their neighboring cellsthrough exosomes in central nervous system diseases. However, the effect of sinomenine on astrocyte-deri...

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Detalles Bibliográficos
Autores principales: Ou, Jinying, Zhou, Yuting, Li, Chan, Chen, Zhijie, Li, Hancheng, Fang, Miao, Zhu, Chen, Huo, Chuying, Yung, Ken Kin-Lam, Li, Jing, Luo, Chaohua, Mo, Zhixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225372/
https://www.ncbi.nlm.nih.gov/pubmed/30227624
http://dx.doi.org/10.3390/molecules23092370