Kinetic Features of 3′-5′ Exonuclease Activity of Human AP-Endonuclease APE1

Human apurinic/apyrimidinic (AP)-endonuclease APE1 is one of the key enzymes taking part in the repair of damage to DNA. The primary role of APE1 is the initiation of the repair of AP-sites by catalyzing the hydrolytic incision of the phosphodiester bond immediately 5′ to the damage. In addition to...

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Detalles Bibliográficos
Autores principales: Kuznetsova, Alexandra A., Fedorova, Olga S., Kuznetsov, Nikita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225374/
https://www.ncbi.nlm.nih.gov/pubmed/30134601
http://dx.doi.org/10.3390/molecules23092101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225374/
https://www.ncbi.nlm.nih.gov/pubmed/30134601
http://dx.doi.org/10.3390/molecules23092101

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