Ferrocene-Containing Impiridone (ONC201) Hybrids: Synthesis, DFT Modelling, In Vitro Evaluation, and Structure–Activity Relationships

Inspired by the well-established clinical evidence about the interplay between apoptotic TRAIL (tumour necrosis factor-related apoptosis-inducing ligand) mechanism and reactive oxygen species (ROS)-mediated oxidative stress, a set of novel ONC201 hybrids containing the impiridone core and one or two...

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Detalles Bibliográficos
Autores principales: Bárány, Péter, Oláh, Rita Szabó, Kovács, Imre, Czuczi, Tamás, Szabó, Csenge Lilla, Takács, Angéla, Lajkó, Eszter, Láng, Orsolya, Kőhidai, László, Schlosser, Gitta, Bősze, Szilvia, Mező, Gábor, Hudecz, Ferenc, Csámpai, Antal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225426/
https://www.ncbi.nlm.nih.gov/pubmed/30177664
http://dx.doi.org/10.3390/molecules23092248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225426/
https://www.ncbi.nlm.nih.gov/pubmed/30177664
http://dx.doi.org/10.3390/molecules23092248

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