HCN Channels: New Therapeutic Targets for Pain Treatment

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are highly regulated proteins which respond to different cellular stimuli. The HCN currents (I(h)) mediated by HCN1 and HCN2 drive the repetitive firing in nociceptive neurons. The role of HCN channels in pain has been widely investi...

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Detalles Bibliográficos
Autores principales: Ramírez, David, Zúñiga, Rafael, Concha, Guierdy, Zúñiga, Leandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225464/
https://www.ncbi.nlm.nih.gov/pubmed/30134541
http://dx.doi.org/10.3390/molecules23092094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225464/
https://www.ncbi.nlm.nih.gov/pubmed/30134541
http://dx.doi.org/10.3390/molecules23092094

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