Synthesis and Antiproliferative Activity of New Cyclodiprenyl Phenols against Select Cancer Cell Lines

Six new cyclodiprenyl phenols were synthesized by direct coupling of perillyl alcohol and the appropriate phenol. Their structures were established by IR, HRMS and mainly NMR. Three human cancer cell lines—breast (MCF-7), prostate (PC-3) and colon (HT-29)—were used in antiproliferative assays, with...

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Detalles Bibliográficos
Autores principales: Said, Bastián, Montenegro, Iván, Valenzuela, Manuel, Olguín, Yusser, Caro, Nelson, Werner, Enrique, Godoy, Patricio, Villena, Joan, Madrid, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225466/
https://www.ncbi.nlm.nih.gov/pubmed/30213053
http://dx.doi.org/10.3390/molecules23092323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225466/
https://www.ncbi.nlm.nih.gov/pubmed/30213053
http://dx.doi.org/10.3390/molecules23092323

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