Brain-targeted delivery of PEGylated nano-bacitracin A against Penicillin-sensitive and -resistant Pneumococcal meningitis: formulated with RVG(29) and Pluronic(®) P85 unimers

Pneumococcal meningitis (PM), caused by Streptococcus pneumonia, remains a high-burden disease in developing countries. Antibiotic therapy has been limited due to the inefficiency of drug transport across the blood-brain barrier (BBB) and the emergence of drug-resistant strains. In our preliminary s...

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Detalles Bibliográficos
Autores principales: Hong, Wei, Zhang, Zehui, Liu, Lipeng, Zhao, Yining, Zhang, Dexian, Liu, Mingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225518/
https://www.ncbi.nlm.nih.gov/pubmed/30404541
http://dx.doi.org/10.1080/10717544.2018.1486473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225518/
https://www.ncbi.nlm.nih.gov/pubmed/30404541
http://dx.doi.org/10.1080/10717544.2018.1486473

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