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Urothelium with barrier function differentiated from human urine-derived stem cells for potential use in urinary tract reconstruction

BACKGROUND: Autologous urothelial cells are often obtained via bladder biopsy to generate the bio-engineered urethra or bladder, while urine-derived stem cells (USC) can be obtained by a non-invasive approach. The objective of this study is to develop an optimal strategy for urothelium with permeabi...

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Detalles Bibliográficos
Autores principales: Wan, Qian, Xiong, Geng, Liu, Guihua, Shupe, Thomas D., Wei, Guanghui, Zhang, Deying, Liang, Dan, Lu, Xiongbing, Atala, Anthony, Zhang, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225683/
https://www.ncbi.nlm.nih.gov/pubmed/30409188
http://dx.doi.org/10.1186/s13287-018-1035-6