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Key genes and integrated modules in hematopoietic differentiation of human embryonic stem cells: a comprehensive bioinformatic analysis

BACKGROUND: The generation of hematopoietic stem cells (HSCs) and blood cells from human embryonic stem cells (hESCs) is a major goal for regenerative medicine; however, the differentiation mechanisms are largely undefined. Here, we aimed to identify the regulated genes and functional modules relate...

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Detalles Bibliográficos
Autores principales: Li, Pengfei, Wu, Mengyao, Lin, Qiwang, Wang, Shu, Chen, Tong, Jiang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225692/
https://www.ncbi.nlm.nih.gov/pubmed/30409225
http://dx.doi.org/10.1186/s13287-018-1050-7