Cargando…
Antagonistic interaction between Nodal and insulin modulates pancreatic β-cell proliferation and survival
BACKGROUND: Insulin signaling pathway in β-cell is essential to promote β-cells proliferation and survival, while Nodal–ALK7–Smad3 signaling involves β-cells apoptosis. We attempted to address inter-relationship between Nodal and insulin in modulating β-cell proliferation and apoptosis. METHODS: Usi...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225724/ https://www.ncbi.nlm.nih.gov/pubmed/30409165 http://dx.doi.org/10.1186/s12964-018-0288-0 |