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TRIM32 overexpression improves chemoresistance through regulation of mitochondrial function in non-small-cell lung cancers

BACKGROUND: TRIM32 is overexpressed in several human cancers. However, its expression pattern, biological characteristics and mechanisms in human non-small cell lung cancer (NSCLC) have not been reported. METHODS: We examined TRIM32 protein in 115 cases of NSCLC specimens. TRIM32 plasmid transfectio...

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Detalles Bibliográficos
Autores principales: Du, Yaming, Zhang, Wei, Du, Binghui, Zang, Sheng, Wang, Xinpeng, Mao, Xin, Hu, Zhansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225845/
https://www.ncbi.nlm.nih.gov/pubmed/30464531
http://dx.doi.org/10.2147/OTT.S176689