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Impact of TP53 mutation status on systemic treatment outcome in ALK-rearranged non-small-cell lung cancer
BACKGROUND: We analyzed whether co-occurring mutations influence the outcome of systemic therapy in ALK-rearranged non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS: ALK-rearranged stage IIIB/IV NSCLC patients were analyzed with next-generation sequencing and fluorescence in situ hybridizatio...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225899/ https://www.ncbi.nlm.nih.gov/pubmed/30165392 http://dx.doi.org/10.1093/annonc/mdy333 |