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Hydralazine HCl rapidly disintegrating sublingual tablets: simple dosage form of higher bioavailability and enhanced clinical efficacy for potential rapid control on hypertensive preeclampsia

BACKGROUND: Hypertensive disorders are the most common complication in pregnancy which can even lead to maternal mortality. Hydralazine hydrochloride (HHC), a direct-acting vasodilator, is intravenously used as the first-line therapy in controlling hypertension in pregnancy (preeclampsia). It suffer...

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Detalles Bibliográficos
Autores principales: Genedy, Samar, Khames, Ahmed, Hussein, Amal, Sarhan, Hatem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225918/
https://www.ncbi.nlm.nih.gov/pubmed/30464406
http://dx.doi.org/10.2147/DDDT.S173326