Gut Barrier Dysfunction—A Primary Defect in Twins with Crohn’s Disease Predominantly Caused by Genetic Predisposition

BACKGROUND AND AIMS: The aetiology of Crohn’s disease is poorly understood. By investigating twin pairs discordant for Crohn’s disease, we aimed to assess whether the dysregulated barrier represents a cause or a consequence of inflammation and to evaluate the impact of genetic predisposition on barr...

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Detalles Bibliográficos
Autores principales: Keita, Åsa V, Lindqvist, Carl Mårten, Öst, Åke, Magana, Carlos D L, Schoultz, Ida, Halfvarson, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225972/
https://www.ncbi.nlm.nih.gov/pubmed/29659773
http://dx.doi.org/10.1093/ecco-jcc/jjy045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225972/
https://www.ncbi.nlm.nih.gov/pubmed/29659773
http://dx.doi.org/10.1093/ecco-jcc/jjy045

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