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Evaluation of the Cardiac Safety of Long‐Acting Endectocide Moxidectin in a Randomized Concentration‐QT Study

Potential effects on cardiac repolarization of single doses of moxidectin, a potent long‐acting macrocyclic lactone endectocide, were assessed in a concentration‐QT (c‐QT; exposure‐response) study. This double‐blind, placebo‐controlled, parallel‐group study in healthy male volunteers (n = 60) random...

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Detalles Bibliográficos
Autores principales: Kinrade, Sally A., Mason, Jay W., Sanabria, Carlos R., Rayner, Craig R., Bullock, Julie M., Stanworth, Stephanie H., Sullivan, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226119/
https://www.ncbi.nlm.nih.gov/pubmed/30117300
http://dx.doi.org/10.1111/cts.12583