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The APOE ε4 allele is associated with a reduction in FEV(1)/FVC in women: A cross-sectional analysis of the Long Life Family Study

INTRODUCTION: Murine studies have shown that apolipoprotein E modulates pulmonary function during development, aging, and allergen-induced airway disease. It is not known whether the polymorphic human APOE gene influences pulmonary function. OBJECTIVES: We assessed whether an association exists betw...

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Detalles Bibliográficos
Autores principales: Kulminski, Alexander M., Barochia, Amisha V., Loika, Yury, Raghavachari, Nalini, Arbeev, Konstantin G., Wojczynski, Mary K., Thyagarajan, Bharat, Vardarajan, Badri N., Christensen, Kaare, Yashin, Anatoliy I., Levine, Stewart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226172/
https://www.ncbi.nlm.nih.gov/pubmed/30412599
http://dx.doi.org/10.1371/journal.pone.0206873