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Comparison of proinsulin and C-peptide secretion in healthy versus long-standing type 1 diabetes mellitus cohorts: A pilot study

AIMS: Increased proinsulin (PI) compared to C-peptide (CP) concentrations have been reported, both prior to type 1 diabetes mellitus (T1D) onset, as well as early in disease. In this pilot study, we sought to define the normal PI secretion in a healthy cohort and compare this to a local T1D cohort a...

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Detalles Bibliográficos
Autores principales: Sullivan, Catherine A., Cacicedo, Jose M., Rajendran, Iniya, Steenkamp, Devin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226191/
https://www.ncbi.nlm.nih.gov/pubmed/30412637
http://dx.doi.org/10.1371/journal.pone.0207065