The yeast stress inducible Ssa Hsp70 reduces α-synuclein toxicity by promoting its degradation through autophagy

The mechanism underlying the role of Hsp70s in toxicity associated with intracellular accumulation of toxic protein inclusions is under intense investigation. In current study, we examined the roles of all different isoforms of yeast cytosolic Ssa Hsp70 on α-synuclein mediated cellular toxicity. The...

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Detalles Bibliográficos
Autores principales: Gupta, Arpit, Puri, Anuradhika, Singh, Prashant, Sonam, Surabhi, Pandey, Richa, Sharma, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226208/
https://www.ncbi.nlm.nih.gov/pubmed/30376576
http://dx.doi.org/10.1371/journal.pgen.1007751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226208/
https://www.ncbi.nlm.nih.gov/pubmed/30376576
http://dx.doi.org/10.1371/journal.pgen.1007751

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