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CIZ1-F, an alternatively spliced variant of the DNA replication protein CIZ1 with distinct expression and localisation, is overrepresented in early stage common solid tumours

CIZ1 promotes cyclin-dependent DNA replication and resides in sub-nuclear foci that are part of the protein nuclear matrix (NM), and in RNA assemblies that are enriched at the inactive X chromosome (Xi) in female cells. It is subjected to alternative splicing, with specific variants implicated in ad...

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Detalles Bibliográficos
Autores principales: Swarts, Dorian R.A., Stewart, Emma R., Higgins, Gillian S., Coverley, Dawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226236/
https://www.ncbi.nlm.nih.gov/pubmed/30280956
http://dx.doi.org/10.1080/15384101.2018.1526600